Knee Pain PVG Staff

Is Genicular Artery Embolization Right for You?

What Is Genicular Artery Embolization?

GAE is a non-surgical procedure that reduces blood flow to the inflamed lining of the knee joint. When osteoarthritis progresses, tiny blood vessels (called genicular arteries) grow and feed inflammation in the joint. GAE blocks these vessels, reducing pain and swelling at the source—without replacing any part of the joint.

It’s an outpatient procedure performed by our board-certified vascular specialists, typically with light sedation and minimal recovery time.

X-ray of a knee joint with inflamed areas highlighted for GAE evaluation

Are You a Good Candidate for GAE?

You’ve Been Diagnosed with Knee Osteoarthritis

If your knee pain is caused by osteoarthritis—especially in the early to moderate stages—GAE may help you delay or avoid surgery altogether. The procedure works best when inflammation is the primary driver of your symptoms, which your doctor can confirm through imaging and a clinical evaluation.

You’re Not Getting Relief from Conservative Treatments

If physical therapy, NSAIDs, braces, and injections haven’t provided lasting relief, GAE offers a meaningful next step before considering surgery. Many patients reach a point where conservative treatments only mask symptoms temporarily. GAE addresses the underlying blood flow patterns that keep inflammation active in the joint.

You’re Not Ready for a Knee Replacement

Whether due to age, lifestyle, or other medical reasons, some people simply aren’t ready for total knee replacement. GAE is joint-preserving, meaning you keep your natural knee. Because the procedure does not alter the joint structure, having GAE does not prevent you from getting a knee replacement later if your condition progresses.

You Want a Shorter Recovery

Knee replacement can require months of intensive rehab. With GAE, most patients return to light activity within a few days. There are no large incisions, no hospital stay, and no need for general anesthesia. Many patients are walking comfortably within 24 to 48 hours and return to their normal routines within a week.

Who Might Not Be a Fit for GAE?

While GAE is a great option for many patients, it’s not right for everyone. You may need to consider other treatments if:

  • You have severe bone-on-bone arthritis with significant joint deformity
  • You have active infections or vascular complications
  • Your pain is caused by issues unrelated to osteoarthritis (e.g., ligament tears)

Your provider will use imaging and a full evaluation to determine if GAE is appropriate for your situation. In these cases, other treatments such as knee replacement surgery or targeted physical therapy may be more suitable.

Patient performing physical therapy exercises for arthritic knee pain management

What to Expect During the GAE Procedure

GAE is designed to be straightforward and comfortable. On the day of your procedure, you’ll receive light sedation and local numbing at the access point, typically the wrist or groin. Your interventional radiologist will insert a very thin catheter into an artery and guide it to the genicular arteries around your knee using real-time imaging. Once the overactive vessels feeding the inflammation are identified, tiny biocompatible particles are released to block them. The entire procedure usually takes one to two hours, and most patients go home the same day.

Comparing GAE to Other Knee Pain Treatments

TreatmentInvasive?Relief DurationRecovery Time
NSAIDsNoShort-termNone
Corticosteroid InjectionsNoWeeks to monthsMinimal
Physical TherapyNoVariesOngoing
GAEMinimally12+ monthsDays
Total Knee ReplacementYesYearsMonths

What Patients Are Saying

Many patients report major improvements in knee pain and quality of life within just a few weeks of the procedure. Some go back to walking, working, and enjoying hobbies they had to give up due to pain—all without surgery.

“Everything went great! The staff was awesome! Dr Rajdev and nurse Morgan were great! They explained everything well.”

— Dawn Reichard

Still Not Sure? Let’s Talk.

At Preferred Vascular Group, we offer GAE consultations at our three Cleveland and Akron, OH locations and our four offices in Atlanta, GA. Our experienced team will review your history, imaging, and symptoms to help you make an informed decision.

Have questions you’d like to discuss before your visit? Please contact us here.

References

  1. Bagla S, et al. “Multicenter Randomized Sham Controlled Study of Genicular Artery Embolization for Knee Pain Secondary to Osteoarthritis.” Journal of Vascular and Interventional Radiology, 2022. Link
  2. Torkian P, et al. “Genicular Artery Embolization for Osteoarthritis Related Knee Pain: A Systematic Review and Qualitative Analysis of Clinical Outcomes.” CardioVascular and Interventional Radiology, 2021. Link
  3. Little MW, Gibson M, et al. “Genicular Artery Embolization for Treatment of Symptomatic Knee Osteoarthritis: 2-Year Outcomes from a Prospective IDE Trial.” Journal of Vascular and Interventional Radiology, 2024. Link

Medically Reviewed By: Maharshi Rajdev, MD

Medical Disclaimer: This content is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider for diagnosis and treatment options specific to your condition.

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